NR4A1 antibody (Ser351)

Catalog No. ABIN7180055

This Rabbit Polyclonal antibody specifically detects NR4A1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for NR4A1 antibody (Ser351) (ABIN7180055)

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR4A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NR4A1 Antibody

Binding Specificity: Ser351

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Alternative Name: NR4A1

Background:

Background: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Nakai A., Mol. Endocrinol. 4:1438-1443(1990).
Chang C., J. Steroid Biochem. 34:391-395(1989).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: Early response protein NAK1 antibody, GFRP 1 antibody, GFRP antibody, GFRP1 antibody, Growth factor inducible nuclear protein N10 antibody, Growth Factor Inducible Nuclear Protein NP10 antibody, Growth Factor Response Protein 1 antibody, Hbr1 antibody, HMR antibody, Hormone Receptor antibody, MGC9485 antibody, N10 antibody, N10 nuclear protein antibody, NAK 1 antibody, NAK1 antibody, Nerve growth factor IB nuclear receptor variant 1 antibody, NGFIB antibody, NP 10 antibody, NP10 antibody, NR4A1 antibody, NR4A1_HUMAN antibody, Nuclear hormone receptor NUR/77 antibody, Nuclear Hormone Receptor TR3 antibody, Nuclear receptor subfamily 4 group A member 1 antibody, NUR77 antibody, NUR77, mouse, homolog of antibody, Orphan nuclear receptor HMR antibody, Orphan nuclear receptor NR4A1 antibody, Orphan nuclear receptor TR3 antibody, Orphan receptor tr3 antibody, Receptor NGFIB antibody, ST 59 antibody, ST-59 antibody, ST59 antibody, Steroid receptor TR3 antibody, Testicular receptor 3 antibody, TR 3 antibody, TR3 antibody, TR3 orphan receptor antibody

UniProt: P22736

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway