ATPBD3 antibody (C-Term)

Catalog No. ABIN7180124

This Rabbit Polyclonal antibody specifically detects ATPBD3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ATPBD3 antibody (C-Term) (ABIN7180124)

Target: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATPBD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ATPBD3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human ATBP3.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATPBD3

Target: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Alternative Name: CTU1

Background:

Background: Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Yousef G.M., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).

Aliases: ATP binding domain 3 antibody, ATP-binding domain-containing protein 3 antibody, Cancer associated protein antibody, Cancer-associated gene protein antibody, ctu1 antibody, CTU1_HUMAN antibody, Cytoplasmic tRNA 2-thiolation protein 1 antibody, Cytoplasmic tRNA adenylyltransferase 1 antibody, Cytosolic thiouridylase subunit 1 homolog antibody, NCS6 antibody

UniProt: Q7Z7A3