KDM4B antibody (C-Term)

Catalog No. ABIN7180190

This Rabbit Polyclonal antibody specifically detects KDM4B in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for KDM4B antibody (C-Term) (ABIN7180190)

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-KDM4B Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human JHD3B.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM4B

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Alternative Name: KDM4B

Background:

Background: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).
Grimwood J., Nature 428:529-535(2004).

Aliases: JHDM3B antibody, JmjC domain-containing histone demethylation protein 3B antibody, JMJD2B antibody, Jumonji domain containing 2B antibody, Jumonji domain containing protein 2B antibody, Jumonji domain-containing protein 2B antibody, Kdm4b antibody, KDM4B_HUMAN antibody, KIAA0876 antibody, Lysine (K) specific demethylase 4B antibody, Lysine demethylase 4B antibody, Lysine-specific demethylase 4B antibody, TDRD14B antibody, Tudor domain containing 14B antibody

UniProt: O94953

Pathways: Warburg Effect