SIRT3 antibody (C-Term)

Catalog No. ABIN7180249

This anti-SIRT3 antibody is a Rabbit Polyclonal antibody detecting SIRT3 in WB and ELISA. Suitable for Human.

Quick Overview for SIRT3 antibody (C-Term) (ABIN7180249)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human SIRT3.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background:

Background: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

Bechtel S., BMC Genomics 8:399-399(2007).
Schwer B., J. Cell Biol. 158:647-657(2002).
Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).

Aliases: hSIRT 3 antibody, hSIRT3 antibody, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase antibody, NAD dependent deacetylase sirtuin 3 mitochondrial antibody, NAD-dependent protein deacetylase sirtuin-3, mitochondrial antibody, Regulatory protein SIR2 homolog 3 antibody, Silent mating type information regulation 2 S.cerevisiae homolog 3 antibody, Sir 2 like 3 antibody, SIR 2 like protein 3 antibody, SIR 3 antibody, SIR2 L3 antibody, Sir2 like 3 antibody, SIR2 like protein 3 antibody, SIR2-like protein 3 antibody, SIR2L3 antibody, SIR3_HUMAN antibody, SIRT 3 antibody, SIRT3 antibody, Sirtuin 3 antibody, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) antibody, Sirtuin type 3 antibody, Sirtuin3 antibody

UniProt: Q9NTG7