Urocortin antibody (C-Term)

Catalog No. ABIN7180283

This Rabbit Polyclonal antibody specifically detects Urocortin in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Urocortin antibody (C-Term) (ABIN7180283)

Target: Urocortin (UCN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Urocortin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Urocortin Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human urocortin.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Urocortin

Target: Urocortin (UCN)

Alternative Name: UCN

Background:

Background: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta.

Kazumi Iino, J. Clin. Endocrinol. Metab., Nov 1997, 82: 3842 - 3850.
Alison C. Holloway, Am J Physiol Endocrinol Metab, Jul 2002, 283: E165 - E171.
Toshio Nishikimi, Am J Physiol Heart Circ Physiol, Dec 2000, 279: 3031.
Stacie C. Weninger, Endocrinolog

Aliases: prepro-urocortin antibody, Ucn antibody, UCN1_HUMAN antibody, UI antibody, UROC antibody, Urocortin antibody, Urocortin precursor antibody, urocortin, preproprotein antibody, Urotensin I antibody

UniProt: P55089

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of Cell Size, Feeding Behaviour