Metabotropic Glutamate Receptor 3 antibody

Catalog No. ABIN7181336

This Rabbit Polyclonal antibody specifically detects Metabotropic Glutamate Receptor 3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Metabotropic Glutamate Receptor 3 antibody (ABIN7181336)

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Metabotropic Glutamate Receptor 3 Antibody

Purpose: GRM3 Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human GluR2/3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Metabotropic Glutamate Receptor 3

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Alternative Name: GRM3

Background:

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Akiko Momiyama, J. Physiol., May 2003, 549: 75 - 92.
Mako Narisawa-Saito, PNAS, Mar 1999, 96: 2461.
Karolina Wosik, Brain, Dec 2004, 127: 2636 - 2648.
Chong-Hyun Kim, PNAS, Sep 2001, 98: 11725.

Aliases: GLUR3 antibody, Glutamate metabotropic receptor 3 antibody, Glutamate receptor metabotropic 3 antibody, GPRC1C antibody, GRM3 antibody, GRM3_HUMAN antibody, Metabotropic glutamate receptor 3 antibody, MGlu3 antibody, mGluR3 antibody

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane