HIST1H3A antibody (AA 120-132)

Catalog No. ABIN7181543

This Rabbit Polyclonal antibody specifically detects HIST1H3A in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for HIST1H3A antibody (AA 120-132) (ABIN7181543)

Target: HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H3A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-HIST1H3A Antibody

Binding Specificity: AA 120-132

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Synthesized peptide derived from Human Histone H3.1 protein (120-132aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:10-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HIST1H3A

Target: HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))

Alternative Name: HIST1H3A

Background:

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Aliases: Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l), HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ

UniProt: P68431