PKC alpha antibody (pThr497)

Catalog No. ABIN7182428

This Rabbit Polyclonal antibody specifically detects PKC alpha in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for PKC alpha antibody (pThr497) (ABIN7182428)

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PKC alpha Antibody

Binding Specificity: pThr497

Purpose: Phospho-PRKCA/PRKCB/PRKCD/PRKCE/PRKCG/PRKCH/PRKCQ/PRKCZ (T497) Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human PKC around the phosphorylation site of T497.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PKC alpha

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Alternative Name: PRKCA

Background: PRKCA, PKCA, PRKACA, Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCB, PKCB, PRKCB1, Protein kinase C beta type, PKC-B, PKC-beta, PRKCD, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, PRKCE, PKCE, Protein kinase

UniProt: P17252, P05771, Q05655, Q02156, P05129, P24723, Q04759, Q05513

Pathways: WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling