FBXW7 antibody

Catalog No. ABIN7183269

Product Details anti-FBXW7 Antibody

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human CDC40.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FBXW7

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Alternative Name: CDC4 (FBXW7 Products)

Background:

Background: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

Zhou Z., EMBO J. 17:2095-2106(1998).
Lindsey L.A., J. Biol. Chem. 273:32771-32775(1998).
Mungall A.J., Nature 425:805-811(2003).

Aliases: Cdc40 antibody, Cell division cycle 40 antibody, Cell division cycle 40 homolog antibody, EH binding protein 3 antibody, EH-binding protein 3 antibody, Ehb3 antibody, hPRP17 antibody, Pre mRNA processing factor 17 antibody, Pre mRNA splicing factor 17 antibody, Pre-mRNA-processing factor 17 antibody, PRP17 antibody, PRP17 homolog antibody, PRP17_HUMAN antibody, PRPF17 antibody

UniProt: O60508

Pathways: Notch Signaling, EGFR Signaling Pathway