CABLES2 antibody (AA 101-200) (HRP)

Catalog No. ABIN714110

The Rabbit Polyclonal anti-CABLES2 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect CABLES2 in samples from Human.

Quick Overview for CABLES2 antibody (AA 101-200) (HRP) (ABIN714110)

Target: CABLES2 (Cdk5 and Abl Enzyme Substrate 2 (CABLES2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABLES2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CABLES2 Antibody (HRP)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CABLES2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CABLES2

Target: CABLES2 (Cdk5 and Abl Enzyme Substrate 2 (CABLES2))

Alternative Name: CABLES2

Background:

Synonyms: CABLES 2, Cdk5 and Abl enzyme substrate 2, Ik3 2 , Interactor with CDK3 2, C20orf150, CABL2_HUMAN.

Background: CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.

Gene ID: 81928