GADD45GIP1 antibody

Catalog No. ABIN7183563

The Rabbit Polyclonal anti-GADD45GIP1 antibody has been validated for ELISA and IHC. It is suitable to detect GADD45GIP1 in samples from Human.

Quick Overview for GADD45GIP1 antibody (ABIN7183563)

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45GIP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-GADD45GIP1 Antibody

Purpose: GADD45GIP1 Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human GADD45GIP1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Alternative Name: GADD45GIP1

Background:

Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Goernemann J., Virology 303:69-78(2002).
Chung H.K., J. Biol. Chem. 278:28079-28088(2003).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: 39S ribosomal protein L59 mitochondrial antibody, CKBBP2 antibody, CKbetaBP2 antibody, CKII beta associating protein antibody, CKII beta binding protein 2 antibody, CKII beta-associating protein antibody, CR6 interacting factor 1 antibody, CR6-interacting factor 1 antibody, CRIF1 antibody, G45IP_HUMAN antibody, GADD45G interacting protein 1 antibody, Gadd45gip1 antibody, Growth arrest and DNA damage inducible GADD45G interacting protein antibody, growth arrest and DNA damage inducible, gamma interacting protein 1 antibody, Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody, MGC4667 antibody, MGC4758 antibody, MRP L59 antibody, p53 responsive gene 6 antibody, p53 responsive gene 6 protein antibody, p53-responsive gene 6 protein antibody, Papillomavirus L2 interacting nuclear protein 1 antibody, Papillomavirus L2-interacting nuclear protein 1 antibody, PLINP 1 antibody, PLINP antibody, PLINP-1 antibody, PLINP1 antibody, PRG6 antibody

UniProt: Q8TAE8