IRX3 antibody
Quick Overview for IRX3 antibody (ABIN7183684)
Target
See all IRX3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from internal of Human IRX3.
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Isotype
- IgG
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Application Notes
- IHC:1:50-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IRX3 (Iroquois Homeobox 3 (IRX3))
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Alternative Name
- IRX3
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Background
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Background: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity.
Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.Aliases: AI894186 antibody, Homeodomain protein IRXB1 antibody, Iroquois class homeodomain protein IRX 1 antibody, Iroquois homeobox 3 antibody, Iroquois homeobox protein 3 antibody, Iroquois-class homeodomain protein irx-3 antibody, IRX 1 antibody, irx3 antibody, IRX3_HUMAN antibody, IRXB1 antibody
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UniProt
- P78415
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Pathways
- Tube Formation
Target
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