MX2 antibody
Quick Overview for MX2 antibody (ABIN7183867)
Target
See all MX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from Internal of Human MX2.
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Isotype
- IgG
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Application Notes
- WB:1:500-1:3000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MX2 (MX dynamin like GTPase 2 (MX2))
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Alternative Name
- MX2
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Background
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Background: Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Aebi M., Mol. Cell. Biol. 9:5062-5072(1989).
Hattori M., Nature 405:311-319(2000).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Aliases: Interferon induced GTP binding protein Mx2 antibody, Interferon regulated resistance GTP binding protein MXB antibody, Interferon-induced GTP-binding protein Mx2 antibody, Interferon-regulated resistance GTP-binding protein MxB antibody, MX 2 antibody, MX dynamin like GTPase 2 antibody, Mx2 antibody, MX2_HUMAN antibody, MXB antibody, Myxovirus (influenza virus) resistance 2 antibody, Myxovirus resistance 2 antibody, Myxovirus resistance protein 2 antibody, p78 related protein antibody, p78-related protein antibody, Second interferon induced protein p78 antibody
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UniProt
- P20592
Target
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