MAPK6 antibody

Catalog No. ABIN7183941

The Rabbit Polyclonal anti-MAPK6 antibody has been validated for WB, ELISA and IF. It is suitable to detect MAPK6 in samples from Human.

Quick Overview for MAPK6 antibody (ABIN7183941)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MAPK6 Antibody

Purpose: MAPK6 Antibody

Cross-Reactivity: Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human p97 MAPK.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: MAPK6

Background:

Background: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle By similarity.

Zhu A.X., Mol. Cell. Biol. 14:8202-8211(1994).
Meloche S., Oncogene 13:1575-1579(1996).
The MGC Project Team, Genome Res. 14:2121-2127(2004)

Aliases: ERK-3 antibody, ERK3 antibody, Extracellular signal regulated kinase 3 antibody, Extracellular signal regulated kinase p97 antibody, Extracellular signal-regulated kinase 3 antibody, HsT17250 antibody, MAP kinase 6 antibody, MAP kinase isoform p97 antibody, MAPK 6 antibody, MAPK6 antibody, Mitogen activated protein kinase 6 antibody, Mitogen-activated protein kinase 6 antibody, MK06_HUMAN antibody, p97 MAPK antibody, p97-MAPK antibody, PRKM6 antibody, Protein kinase mitogen activated 5 antibody, Protein kinase mitogen activated 6 antibody

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C