ZIC1 antibody

Catalog No. ABIN7184361

The Rabbit Polyclonal anti-ZIC1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ZIC1 in samples from Human.

Quick Overview for ZIC1 antibody (ABIN7184361)

Target: ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ZIC1 Antibody

Purpose: ZIC1 Antibody

Cross-Reactivity: Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human ZIC1/2/3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ZIC1

Target: ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))

Alternative Name: ZIC1

Background:

Background: Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' By similarity.

Yokota N., Cancer Res. 56:377-383(1996).

Aliases: Odd paired homolog Drosophila antibody, Zic 1 antibody, ZIC antibody, Zic family member 1 (odd-paired Drosophila homolog) antibody, Zic family member 1 antibody, Zic protein member 1 antibody, zic1 antibody, ZIC1_HUMAN antibody, Zinc finger protein 201 antibody, Zinc finger protein of the cerebellum 1 antibody, Zinc finger protein ZIC 1 antibody, Zinc finger protein ZIC1 antibody, ZNF 201 antibody, ZNF201 antibody

UniProt: Q15915