MKL1 antibody (N-Term)

Catalog No. ABIN7184480

This Rabbit Polyclonal antibody specifically detects MKL1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MKL1 antibody (N-Term) (ABIN7184480)

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MKL1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human MKL1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Alternative Name: MKL1

Background:

Background: Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases, its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.

Ma Z., Nat. Genet. 28:220-221(2001).
Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).
Nagase T., DNA Res. 7:65-73(2000).

Aliases: AI852829 antibody, AMKL antibody, AW743281 antibody, AW821984 antibody, Basic SAP coiled-coil transcription activator antibody, Bsac antibody, KIAA1438 antibody, Mal antibody, Megakaryoblastic leukemia 1 protein antibody, Megakaryocytic acute leukemia protein antibody, MKL (megakaryoblastic leukemia)/myocardin like 1 antibody, MKL/myocardin like protein 1 antibody, MKL/myocardin-like protein 1 antibody, Mkl1 antibody, MKL1_HUMAN antibody, MRTF A antibody, Mrtf A antibody, MRTF-A antibody, MRTFA antibody, MYOCARDIN RELATED PROTEIN antibody, Myocardin related transcription factor A antibody, Myocardin-related transcription factor A antibody

UniProt: Q969V6