RGS12 antibody (N-Term)

Catalog No. ABIN7184501

This Rabbit Polyclonal antibody specifically detects RGS12 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for RGS12 antibody (N-Term) (ABIN7184501)

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS12 Antibody

Binding Specificity: N-Term

Purpose: RGS12 Antibody

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human RGS12.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS12

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Alternative Name: RGS12

Background:

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. soform 5:Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.

Chatterjee T.K., J. Biol. Chem. 275:29660-29671(2000).
Snow B.E., J. Biol. Chem. 273:17749-17755(1998).
Hillier L.W., Nature 434:724-731(2005).

Aliases: RGS12 antibody, Regulator of G-protein signaling 12 antibody, RGS12 antibody

UniProt: O14924

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling