RGS12 antibody (AA 110-190)

Catalog No. ABIN7224014

This Rabbit Polyclonal antibody specifically detects RGS12 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RGS12 antibody (AA 110-190) (ABIN7224014)

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RGS12 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-RGS12 Polyclonal Antibody

Specificity: RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human RGS12 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RGS12

Target: RGS12 (Regulator of G-Protein Signalling 12 (RGS12))

Alternative Name: RGS12

Background: RGS12, Regulator of G-protein signaling 12, RGS12RGS12 (regulator of G-protein signaling 12) encodes a member of the regulator of G protein signaling (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for RGS12. Other alternative splice variants have been described but their biological nature has not been determined.

Molecular Weight: 160kD

Gene ID: 6002

UniProt: O14924

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling