RETNLB antibody (AA 24-80)

Catalog No. ABIN714551

The Rabbit Polyclonal anti-RETNLB antibody is suitable to detect RETNLB in samples from Human. It has been validated for WB, ELISA, IF (p), IF (cc), IHC (p) and IHC (fro).

Quick Overview for RETNLB antibody (AA 24-80) (ABIN714551)

Target: RETNLB (Resistin Like beta (RETNLB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RETNLB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RETNLB Antibody

Binding Specificity: AA 24-80

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RELM beta/CCGR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RETNLB

Target: RETNLB (Resistin Like beta (RETNLB))

Alternative Name: RELM beta

Background:

Synonyms: Resistin like protein beta, C/EBP epsilon regulated myeloid specic secreted cysteine rich protein precursor 2, CCGR, Colon and small intestine specic cysteine rich protein, Colon and small intestine-specic cysteine-rich protein, Colon carcinoma related gene protein, Colon carcinoma-related gene protein, Cysteine rich secreted A12 alpha like protein 1, Cysteine rich secreted protein A12 alpha like 1, Cysteine rich secreted protein FIZZ2, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, FIZZ1, FIZZ2, Found in inflammatory zone 1, Found in Inflammatory Zone 2, HXCP2, RELM beta, RELMb, RELMbeta, Resistin like beta, Resistin Like Protein Beta, Resistin-like beta, RETNB_HUMAN, RETNL2. RETNLB, XCP2.

Background: The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Gene ID: 84666

Pathways: Hormone Activity