LEFTY2 antibody (AA 281-366)

Catalog No. ABIN714611

The Rabbit Polyclonal anti-LEFTY2 antibody has been validated for WB, ELISA, IHC (p), FACS, IF (cc), IF (p) and IHC (fro). It is suitable to detect LEFTY2 in samples from Human.

Quick Overview for LEFTY2 antibody (AA 281-366) (ABIN714611)

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LEFTY2 Antibody

Binding Specificity: AA 281-366

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TGFB4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LEFTY2

Target: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Alternative Name: TGFB4

Background:

Synonyms: EBAF, Endometrial bleeding associated factor left right determination factor A transforming growth factor beta superfamily, Endometrial bleeding associated factor, Endometrial bleeding-associated factor, Left right determination factor 2, Left right determination factor A, Left-right determination factor 2, Left-right determination factor A, LEFTA, LEFTY 2, LEFTY2, LEFTYA, LFTY2_HUMAN, MGC46222, Protein lefty 2, Protein lefty A, Protein lefty-2, Protein lefty-A, Protein lefty2, PSEC0024, TGF beta 4, TGF-beta-4, TGFB4, Transforming growth factor beta 4, Transforming growth factor beta-4.

Background: LEFTY2 is a member of the TGF-beta family of proteins. LEFTY2 is secreted and plays a role in left-right asymmetry determination of organ systems during development and may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene ID: 7044