Exendin 4 antibody

Catalog No. ABIN7189562

The Rabbit Polyclonal anti-Exendin 4 antibody is suitable to detect Exendin 4 in samples from Gila monster. It has been validated for ELISA.

Quick Overview for Exendin 4 antibody (ABIN7189562)

Target: Exendin 4

Reactivity: Gila monster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exendin 4 antibody is un-conjugated

Application: ELISA

Product Details anti-Exendin 4 Antibody

Purpose: Exendin-4 Antibody

Cross-Reactivity: Gila monster

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Heloderma suspectum Exendin 4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Exendin 4

Target: Exendin 4

Alternative Name: Exendin-4

Background:

Background: Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.

Aliases: Exendin-4 antibody, Exenatide antibody

UniProt: P26349