ABCB11 antibody

Catalog No. ABIN7189581

The Rabbit Polyclonal anti-ABCB11 antibody (ABIN7189581) specifically detects ABCB11 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for ABCB11 antibody (ABIN7189581)

Target: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB11 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-ABCB11 Antibody

Purpose: ABCB11 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human ABCB11

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ABCB11

Target: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Alternative Name: ABCB11

Background:

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Aliases: ABC member 16, MDR/TAP subfamily antibody, ABC16 antibody, ABCB1 antibody, Abcb11 antibody, ABCBB_HUMAN antibody, ATP binding cassette sub family B (MDR/TAP) member 11 antibody, ATP binding cassette sub family B member 11 antibody, ATP-binding cassette sub-family B member 11 antibody, Bile salt export pump antibody, BRIC2 antibody, Bsep antibody, PFIC 2 antibody, PFIC2 antibody, PGY4 antibody, progressive familial intrahepatic cholestasis 2 antibody, Sister of P glycoprotein antibody, Spgp antibody

UniProt: O95342