AD7C-NTP antibody

Catalog No. ABIN7189642

This Rabbit Polyclonal antibody specifically detects AD7C-NTP in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for AD7C-NTP antibody (ABIN7189642)

Target: AD7C-NTP

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AD7C-NTP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AD7C-NTP Antibody

Purpose: AD7C-NTP Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human AD7C-NTP

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AD7C-NTP

Target: AD7C-NTP

Background:

Background: The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.

Aliases: Neuronal thread protein AD7c-NTP