ADPRHL2 antibody

Catalog No. ABIN7189696

This Rabbit Polyclonal antibody specifically detects ADPRHL2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ADPRHL2 antibody (ABIN7189696)

Target: ADPRHL2 (ADP-Ribosylhydrolase Like 2 (ADPRHL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADPRHL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADPRHL2 Antibody

Purpose: ADPRHL2 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human ADPRHL2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADPRHL2

Target: ADPRHL2 (ADP-Ribosylhydrolase Like 2 (ADPRHL2))

Alternative Name: ADPRHL2

Background:

Background: This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.

Aliases: [Protein ADP ribosylarginine] hydrolase like protein 2 antibody, [Protein ADP-ribosylarginine] hydrolase-like protein 2 antibody, ADP ribosylhydrolase 3 antibody, ADP ribosylhydrolase like 2 antibody, ADP-ribosylhydrolase 3 antibody, Adprhl2 antibody, AI836109 antibody, ARH3 antibody, ARHL2_HUMAN antibody, ecto ADP ribosylhydrolase antibody, FLJ20446 antibody, OTTMUSP00000009757 antibody, Poly(ADP ribose) glycohydrolase ARH3 antibody, Poly(ADP-ribose) glycohydrolase ARH3 antibody, Protein ADP ribosylarginine hydrolase like protein 2 antibody, RP23-113P22.3 antibody

UniProt: Q9NX46