ALX4 antibody

Catalog No. ABIN7189784

The Rabbit Polyclonal anti-ALX4 antibody has been validated for ELISA and IHC. It is suitable to detect ALX4 in samples from Human.

Quick Overview for ALX4 antibody (ABIN7189784)

Target: ALX4 (ALX Homeobox 4 (ALX4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALX4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ALX4 Antibody

Purpose: ALX4 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human ALX4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ALX4

Target: ALX4 (ALX Homeobox 4 (ALX4))

Alternative Name: ALX4

Background:

Background: This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

Aliases: Alx4 antibody, ALX4_HUMAN antibody, Aristaless like homeobox 4 antibody, CRS5 antibody, FND2 antibody, FPP antibody, homeobox protein aristaless like 4 antibody, Homeobox protein aristaless-like 4 antibody, homeodomain transcription factor ALX4 antibody, KIAA1788 antibody, PFM1 antibody, PFM2 antibody

UniProt: Q9H161