BRWD1 antibody

Catalog No. ABIN7190020

This Rabbit Polyclonal antibody specifically detects BRWD1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for BRWD1 antibody (ABIN7190020)

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRWD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-BRWD1 Antibody

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human BRWD1

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:20-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BRWD1

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Alternative Name: BRWD1

Background:

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Aliases: bromodomain and WD repeat domain containing 1

UniProt: Q9NSI6