CHRNA3 antibody

Catalog No. ABIN7190258

The Rabbit Polyclonal anti-CHRNA3 antibody is suitable to detect CHRNA3 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for CHRNA3 antibody (ABIN7190258)

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CHRNA3 Antibody

Purpose: CHRNA3 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human CHRNA3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRNA3

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Alternative Name: CHRNA3

Background:

Background: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Aliases: ACHA3_HUMAN antibody, AChR antibody, Cholinergic receptor neuronal nicotinic alpha polypeptide 3 antibody, Cholinergic receptor nicotinic alpha 3 antibody, Cholinergic receptor nicotinic alpha polypeptide 3 antibody, CHRNA 3 antibody, CHRNA3 antibody, LNCR2 antibody, MGC104879 antibody, NACHRA 3 antibody, NACHRA3 antibody, Neuronal acetylcholine receptor protein alpha 3 chain precursor antibody, Neuronal acetylcholine receptor subunit alpha 3 antibody, Neuronal acetylcholine receptor subunit alpha-3 antibody, Neuronal nicotinic acetylcholine receptor alpha 3 subunit antibody, PAOD2 antibody

UniProt: P32297

Pathways: Synaptic Membrane