alpha Defensin 1 antibody

Catalog No. ABIN7190455

This Rabbit Polyclonal antibody specifically detects alpha Defensin 1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for alpha Defensin 1 antibody (ABIN7190455)

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Defensin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-alpha Defensin 1 Antibody

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human DEFA1

Isotype: IgG

Application Details

Application Notes: ELISA:1:500-1:5000, WB:1:500-1:1000, IHC:1:25-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for alpha Defensin 1

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Alternative Name: DEFA1

Background:

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Aliases: alpha 1 antibody, DEF1 antibody, DEF1_HUMAN antibody, DEFA1 antibody, DEFA1B antibody, DEFA2 antibody, Defensin 1 antibody, Defensin antibody, Defensin, alpha 1 antibody, Defensin, alpha 1, myeloid related sequence antibody, Defensin, alpha 2 antibody, HNP-1 antibody, HNP-2 antibody, HNP1 antibody, HP-1 antibody, HP-2 antibody, HP1 antibody, HP2 antibody, MRS antibody, Myeloid related sequence antibody, Neutrophil defensin 1 antibody, Neutrophil defensin 2 antibody

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin