MARVELD1 antibody

Catalog No. ABIN7191408

This anti-MARVELD1 antibody is a Rabbit Polyclonal antibody detecting MARVELD1 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for MARVELD1 antibody (ABIN7191408)

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARVELD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MARVELD1 Antibody

Purpose: MARVELD1 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human MARVELD1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MARVELD1

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Alternative Name: MARVELD1

Background:

Background: MARVELD1 (MARVEL domain containing 1), also known as GB14, MARVD1 or MRVLDC1, is a 173 amino acid protein that is widely expressed and contains one MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. The MARVEL domain, which is common in Occludin proteins, is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. Localizing to the nucleus, MARVELD1 is downregulated in primary multiple tumors of liver, bladder, ovary, vulva, breast, testis, uterus, kidney and testis. The gene encoding MARVELD1 maps to human chromosome 10, which makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome and Cowden syndrome.

Aliases: GB14 antibody, MALD1_HUMAN antibody, MARVD1 antibody, MARVEL (membrane-associating) domain containing 1 antibody, MARVEL domain containing protein 1 antibody, MARVEL domain-containing protein 1 antibody, MARVELD1 antibody, MRVLDC1 antibody, Putative MARVEL domain containing protein 1 antibody

UniProt: Q9BSK0