MARVELD1 antibody (AA 31-130)

Catalog No. ABIN717911

The Rabbit Polyclonal anti-MARVELD1 antibody is suitable to detect MARVELD1 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for MARVELD1 antibody (AA 31-130) (ABIN717911)

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARVELD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MARVELD1 Antibody

Binding Specificity: AA 31-130

Purpose: MARVELD1 Polyclonal Antibody

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARVELD1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MARVELD1

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Alternative Name: MARVELD1

Background:

Synonyms: GB14, MARVD1, MARVEL membrane-associating domain containing 1, MARVEL domain containing protein 1, MRVLDC1, Putative MARVEL domain containing protein 1, MALD1_HUMAN.

Background: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Gene ID: 83742