MT-ND3 antibody

Catalog No. ABIN7191523

This Rabbit Polyclonal antibody specifically detects MT-ND3 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for MT-ND3 antibody (ABIN7191523)

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ND3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MT-ND3 Antibody

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human MT-ND3

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MT-ND3

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Alternative Name: MT-ND3

Background:

Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.

Aliases: MT-ND3 antibody, MTND3 antibody, NADH3 antibody, ND3NADH-ubiquinone oxidoreductase chain 3 antibody, EC 7.1.1.2 antibody, NADH dehydrogenase subunit 3 antibody

UniProt: P03897