SEZ6L antibody
Quick Overview for SEZ6L antibody (ABIN7192337)
Target
See all SEZ6L AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- SEZ6L Antibody
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Cross-Reactivity
- Mouse
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of Human SEZ6L
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))
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Alternative Name
- SEZ6L
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Background
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Background: SEZ6L (seizure related 6 homolog-like) is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi (CCP/SCR) domains, which may be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Aliases: SEZ6L antibody, KIAA0927 antibody, UNQ2542/PRO6094Seizure 6-like protein antibody
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UniProt
- Q9BYH1
Target
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