SPRN antibody
Quick Overview for SPRN antibody (ABIN7192636)
Target
See all SPRN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of Human SPRN
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Isotype
- IgG
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Application Notes
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SPRN (Shadow of Prion Protein (SPRN))
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Alternative Name
- SPRN
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Background
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Background: SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may act as a modulator for the biological actions of normal and abnormal PrP. In humans, mutations in the gene encoding SPRN may be associated with variant and sporadic Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal.
Aliases: SPRN antibody, SHO antibody, Shadow of prion protein antibody, Protein shadoo antibody
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UniProt
- Q5BIV9
Target
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