Caspase 3 antibody (Cleaved-Ala175)

Catalog No. ABIN7193153

The Rabbit Polyclonal anti-Caspase 3 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Caspase 3 in samples from Human.

Quick Overview for Caspase 3 antibody (Cleaved-Ala175) (ABIN7193153)

Target: Caspase 3 (CASP3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Caspase 3 Antibody

Binding Specificity: Cleaved-Ala175

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caspase 3

Target: Caspase 3 (CASP3)

Alternative Name: CASP3

Background:

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

Aliases: A830040C14Rik antibody, Apopain antibody, CASP 3 antibody, CASP-3 antibody, CASP3 antibody, CASP3_HUMAN antibody, Casp3a antibody, Caspase 3 antibody, Caspase 3, apoptosis-related cysteine peptidase antibody, Caspase 3, apoptosis-related cysteine protease antibody, Caspase 3, apoptosis-related cysteine protease a antibody, Caspase-3 subunit p12 antibody, Caspase3 antibody, CC3 antibody, CPP 32 antibody, CPP-32 antibody, CPP32 antibody, CPP32B antibody, Cysteine protease CPP32 antibody, EC 3.4.22.56 antibody, ICE3 antibody, LICE antibody, mldy antibody, OTTHUMP00000165052 antibody, OTTHUMP00000165053 antibody, OTTHUMP00000165054 antibody, PARP cleavage protease antibody, Procaspase3 antibody, Protein Yama antibody, SCA 1 antibody, SCA-1 antibody, SCA1 antibody, SREBP cleavage activity 1 antibody, Yama antibody, Yama protein antibody

UniProt: P42574

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation