S1PR1 antibody

Catalog No. ABIN7193259

The Mouse Monoclonal anti-S1PR1 antibody (Clone 8E4H5) (ABIN7193259) specifically detects S1PR1 in WB, ELISA, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for S1PR1 antibody (ABIN7193259)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 8E4H5

Product Details anti-S1PR1 Antibody

Purpose: CD363 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD363 expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: CD363

Background:

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

Molecular Weight: 42.8 kDa

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2