SIGLEC5 antibody (AA 17-230)

Catalog No. ABIN7193301

This anti-SIGLEC5 antibody is a Mouse Monoclonal antibody detecting SIGLEC5 in ELISA and FACS. Suitable for Human.

Quick Overview for SIGLEC5 antibody (AA 17-230) (ABIN7193301)

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC5 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 3F5A3

Product Details anti-SIGLEC5 Antibody

Binding Specificity: AA 17-230

Purpose: CD170 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD170 (AA: 17-230) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SIGLEC5

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Alternative Name: CD170

Background:

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Molecular Weight: 60.7 kDa

Gene ID: 8778

UniProt: O15389