IL5RA antibody (AA 21-196)

Catalog No. ABIN7193317

This Mouse Monoclonal antibody specifically detects IL5RA in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for IL5RA antibody (AA 21-196) (ABIN7193317)

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL5RA antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 5E12F5D6

Product Details anti-IL5RA Antibody

Binding Specificity: AA 21-196

Purpose: CD125 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD125 (AA: 21-196) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Alternative Name: CD125

Background:

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Molecular Weight: 47.7 kDa

Gene ID: 3568

Pathways: JAK-STAT Signaling