ICOSLG antibody (AA 19-256)

Catalog No. ABIN7193325

The Mouse Monoclonal anti-ICOSLG antibody (Clone 1G6E1) (ABIN7193325) specifically detects ICOSLG in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for ICOSLG antibody (AA 19-256) (ABIN7193325)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1G6E1

Product Details anti-ICOSLG Antibody

Binding Specificity: AA 19-256

Purpose: CD275 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD275 (AA: 19-256) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: CD275

Background:

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

Molecular Weight: 33.3 kDa

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation