CLEC7A antibody (AA 66-247)

Catalog No. ABIN7193336

Product Details anti-CLEC7A Antibody

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Binding Specificity: AA 66-247

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLEC7A antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Purpose: CD369 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD369 (AA: 66-247) expressed in E. Coli.

Clone: 4G2G6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CLEC7A

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Alternative Name: CD369 (CLEC7A Products)

Background:

Description:

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Aliases: CLEC7A, BGR, CANDF4, SCARE2, DECTIN1, CLECSF12

Molecular Weight: 27.6kDa

Gene ID: 64581

UniProt: Q9BXN2

Pathways: Activation of Innate immune Response