FUT3 antibody (AA 199-361)

Catalog No. ABIN7193351

The Mouse Monoclonal anti-FUT3 antibody has been validated for ELISA and FACS. It is suitable to detect FUT3 in samples from Human.

Quick Overview for FUT3 antibody (AA 199-361) (ABIN7193351)

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FUT3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1F8G5C7

Product Details anti-FUT3 Antibody

Binding Specificity: AA 199-361

Purpose: CD174 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD174 (AA: 199-361) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for FUT3

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Alternative Name: CD174

Background:

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Molecular Weight: 42.1 kDa

Gene ID: 2525

UniProt: P21217