NFKB2 antibody (AA 712-900)

Catalog No. ABIN7193353

Product Details anti-NFKB2 Antibody

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Binding Specificity: AA 712-900

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NFKB2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: NFKB2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NFKB2 (AA: 712-900) expressed in E. Coli.

Clone: 2F10A7

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for NFKB2

Target: NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))

Alternative Name: NFKB2 (NFKB2 Products)

Background:

Description:

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Aliases: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100

Molecular Weight: 96.7kDa

Gene ID: 4791

UniProt: Q00653

Pathways: Toll-Like Receptors Cascades