IGF2R antibody (AA 160-311)

Catalog No. ABIN7193356

This Mouse Monoclonal antibody specifically detects IGF2R in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for IGF2R antibody (AA 160-311) (ABIN7193356)

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF2R antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4F1G1

Product Details anti-IGF2R Antibody

Binding Specificity: AA 160-311

Purpose: CD222 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Alternative Name: CD222

Background:

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Molecular Weight: 274 kDa

Gene ID: 3482

UniProt: P11717