KAT6B antibody (AA 1186-1318)

Catalog No. ABIN7193390

The Mouse Monoclonal anti-KAT6B antibody has been validated for ELISA. It is suitable to detect KAT6B in samples from Human.

Quick Overview for KAT6B antibody (AA 1186-1318) (ABIN7193390)

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KAT6B antibody is un-conjugated

Application: ELISA

Clone: 8C8D12

Product Details anti-KAT6B Antibody

Binding Specificity: AA 1186-1318

Purpose: KAT6B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KAT6B

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Alternative Name: KAT6B

Background:

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Molecular Weight: 231.4 kDa

Gene ID: 23522

UniProt: Q8WYB5