KDM2A antibody (AA 1-150)

Catalog No. ABIN7193407

This Mouse Monoclonal antibody specifically detects KDM2A in ELISA. It exhibits reactivity toward Human.

Quick Overview for KDM2A antibody (AA 1-150) (ABIN7193407)

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KDM2A antibody is un-conjugated

Application: ELISA

Clone: 5C11F7

Product Details anti-KDM2A Antibody

Binding Specificity: AA 1-150

Purpose: KDM2A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Alternative Name: KDM2A

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Molecular Weight: 132.8 kDa

Gene ID: 22992

UniProt: Q9Y2K7

Pathways: Warburg Effect