WDFY3 antibody (AA 3277-3526)

Catalog No. ABIN7193433

The Mouse Monoclonal anti-WDFY3 antibody (Clone 2F7C2) (ABIN7193433) specifically detects WDFY3 in ELISA, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for WDFY3 antibody (AA 3277-3526) (ABIN7193433)

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WDFY3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2F7C2

Product Details anti-WDFY3 Antibody

Binding Specificity: AA 3277-3526

Purpose: WDFY3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human WDFY3 (AA: 3277-3526) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Alternative Name: WDFY3

Background:

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Molecular Weight: 395 kDa