14-3-3 theta antibody (AA 1-245)

Catalog No. ABIN7193435

The Mouse Monoclonal anti-14-3-3 theta antibody has been validated for WB and ELISA. It is suitable to detect 14-3-3 theta in samples from Human, Mouse, Rat and Monkey.

Quick Overview for 14-3-3 theta antibody (AA 1-245) (ABIN7193435)

Target: 14-3-3 theta (YWHAQ)

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This 14-3-3 theta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5C4E7

Product Details anti-14-3-3 theta Antibody

Binding Specificity: AA 1-245

Purpose: YWHAQ Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human YWHAQ (AA: 1-245) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Alternative Name: YWHAQ

Background:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

Molecular Weight: 27.8 kDa

UniProt: P27348

Pathways: Apoptosis, Myometrial Relaxation and Contraction