COL1A1 antibody (AA 1219-1464)

Catalog No. ABIN7193472

This anti-COL1A1 antibody is a Mouse Monoclonal antibody detecting COL1A1 in ELISA and FACS. Suitable for Human.

Quick Overview for COL1A1 antibody (AA 1219-1464) (ABIN7193472)

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This COL1A1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 7B1G12

Product Details anti-COL1A1 Antibody

Binding Specificity: AA 1219-1464

Purpose: COL1A1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human COL1A1 (AA: 1219-1464) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for COL1A1

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Alternative Name: COL1A1

Background:

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Molecular Weight: 139 kDa

Gene ID: 1277

UniProt: P02452

Pathways: Sensory Perception of Sound, Autophagy, Growth Factor Binding