TUBB3 antibody

Catalog No. ABIN7193512

This Mouse Monoclonal antibody specifically detects TUBB3 in WB, IHC, ELISA and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for TUBB3 antibody (ABIN7193512)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 8E3A7

Product Details anti-TUBB3 Antibody

Purpose: TUBB3 Antibody

Purification: Purified antibody

Immunogen: 436-450:cMYEDDEEESEAQGPK

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3

Background:

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants.

Molecular Weight: 50 kDa

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase