CD163 antibody (AA 42-259)

Catalog No. ABIN7193514

This anti-CD163 antibody is a Mouse Monoclonal antibody detecting CD163 in WB, IHC, FACS and ELISA. Suitable for Human and Mouse.

Quick Overview for CD163 antibody (AA 42-259) (ABIN7193514)

Target: CD163

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Clone: 7G5E2

Product Details anti-CD163 Antibody

Binding Specificity: AA 42-259

Purpose: CD163 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD163 (AA: 42-259) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background:

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 125.4 kDa

Gene ID: 9332

UniProt: Q86VB7