L1CAM antibody (AA 20-197)

Catalog No. ABIN7193538

This anti-L1CAM antibody is a Mouse Monoclonal antibody detecting L1CAM in FACS and ELISA. Suitable for Human.

Quick Overview for L1CAM antibody (AA 20-197) (ABIN7193538)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This L1CAM antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: 5C6A10

Product Details anti-L1CAM Antibody

Binding Specificity: AA 20-197

Purpose: CD171 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD171 (AA: 20-197) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Alternative Name: CD171

Background:

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Molecular Weight: 140 kDa

Gene ID: 3897

UniProt: P32004

Pathways: Synaptic Membrane